Hyaluronic acid-based scaffold for central neural tissue engineering
نویسندگان
چکیده
منابع مشابه
Hyaluronic acid-based scaffold for central neural tissue engineering.
Central nervous system (CNS) regeneration with central neuronal connections and restoration of synaptic connections has been a long-standing worldwide problem and, to date, no effective clinical therapies are widely accepted for CNS injuries. The limited regenerative capacity of the CNS results from the growth-inhibitory environment that impedes the regrowth of axons. Central neural tissue engi...
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Three-dimensional biodegradable porous scaffolds play vital roles in tissue engineering. In this study, a hyaluronic acid-collagen (HA-Coll) sponge with an open porous structure and mechanical behavior comparable to brain tissue was developed. HA-Coll scaffolds with different mixing ratios were prepared by a freeze-drying technique and crosslinked with water-soluble carbodiimide to improve mech...
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ژورنال
عنوان ژورنال: Interface Focus
سال: 2012
ISSN: 2042-8898,2042-8901
DOI: 10.1098/rsfs.2012.0016